Definition
(the laboratory) of his: his (laboratory), (the laboratory) that belongs to him
of his is used after a noun to emphasize possession.
I've no idea what he's doing in that room of his. I know it's his room but we never know what he does in there.
- "It's Horatio's 102nd birthday next Thursday, and I wanted to do something special for him. He is one of my closest friends and sometimes I get the impression that he is lonely in that laboratory of his."
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