Definition
You know nothing!: You do not know anything! You do not have any knowledge!
Anything and nothing are respectively used in negative and affirmative constructions (to avoid a double negative):
I need nothing! I do not need anything! There is nothing that I need!
You don't know anything!: You know nothing! You do not have any knowledge!
I don't need anything! I need nothing! There isn't anything that I need!
- "-Nothing. Unless you're crooked."
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